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Re: Little more

Posted by SLS on May 14, 2009, at 10:25:40

In reply to Re: Little more, posted by linkadge on May 14, 2009, at 8:27:34

> And some studies have demonstrated increased binding.
>
> http://www.futurepundit.com/archives/001768.html

This can make sense. I almost hate to say something so simplistic, but a chronic decrease in available serotonin might force these 5-HT1a somatodendritic autoreceptors to become upregulated. I don't know. I don't know enough about the dynamics of this receptor to be certain. However, if this is true, then you have a positive feedback loop that allows the severity of symptoms to worsen over time.


- Scott

 

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