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Re: Antidepressants Hardly Help ?????????

Posted by SLS on May 11, 2009, at 5:56:32

In reply to Re: Antidepressants Hardly Help ?????????, posted by greywolf on May 11, 2009, at 2:58:11

This claim comes up every so often.

It is untenable.

The article is almost as flawed as the studies it cites. The selection procedure for subjects used in clinical trials of antidepressants almost never includes a diagnostic processing of each candidate thoroughly enough to conclude with certainty that the investigators are treating the right disease - major depressive disorder (MDD) or bipolar disorder (BD). That's why it is so often observed that the more severe depressions benefit the most. A much higher proportion of these subjects have the genuine diseases being investigated. Of course, this does not indicate that less severe cases of MDD or BD respond to treatment. It is just that severe cases are more likely to be the real thing when selection criteria are so liberally inclusive.

These drugs work. It seems misanthropic to me that certain people should set out to prove otherwise.


- Scott

 

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