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Lower-dose Emsam selective for MAOb

Posted by uncouth on May 1, 2009, at 12:06:58

hi there,

as i'm on a whole portfolio of antidepressants and etc. drugs, (milnacipran, tianeptine, nortriptyline, geodon, amantadine, memantine, agomelatine, rilutek, lithium, deplin) for my highly-treatment-resistant, suicidally-deep depression, and i'm still not seeing results (although I have only been on half these drugs for 2 weeks), I want to add yet another drug to the mix.

I have some old Emsam patches 12mg (highest dose) from a failed med trial a while back that I'd like to use to give me some Selegiline boost. What's the maximum I can take (cut the patch size down to) such that I'll be hitting only MAOB and not MAOA which would send me to the hospital given the other things I'm on.

I'm thinking that splitting the 12mg patch into 3, so each segment delivers 4mg of 24 hours, would be OK and only knock out MAOB. Since the lowest available dose of Emsam is 6mg, and I'd assume even the lowest dose of Emsam would be hitting MAOA and MAOB, I figure 4mg gives me enough of a safety room so I don't potentially give myself serotonin syndrome or worse.

I hope this post makes sense and the question I'm asking is sensible.

Love,
Al
<start vent>
P.S. and if that's not enough, I've also got Lamotrigine, Donepezil, and oral Deprenyl on order to add to my mix. F*cking sh*t I hate this illness. I figure i'm giving it a month after being on this whole portfolio of meds, and finishing up my course of ECT (i'm on shock #21 and still not fully better) and I"m either gonna get better TO THE MAX, or just decide to kill myself becuase I will have lost hope after trying essentially every psych med known to be somewhat useful.
ok <end vent>

 

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poster:uncouth thread:893727
URL: http://www.dr-bob.org/babble/20090426/msgs/893727.html