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Re: How much time for the MAO Inhibition? » SLS

Posted by tepi on April 25, 2009, at 18:48:03

In reply to Re: How much time for the MAO Inhibition? » tepi, posted by SLS on April 23, 2009, at 22:38:29


>
> Wild guess - 10-14 days at a steady dosage?
>
> Definitely not 4-8 weeks.
>
> After you reach the percentage of inhibition that is right for you, you need to expect to remain there for 3 weeks to see some improvement. This may represent the time necessary for the compensatory changes that occur in receptor binding. There is approximately a 2 week turnover in receptors, so one might suspect changes in receptor numbers to be involved in the antidepressant response, and why that response is latent to the initial drug exposure.
>
>
> - Scott


Scoot do you think that using higher dosages per day can make this time a little shorter?


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poster:tepi thread:892451
URL: http://www.dr-bob.org/babble/20090416/msgs/892776.html