Posted by linkadge on April 20, 2009, at 10:03:18
In reply to Re: Effects of long term SSRI use... My Story... » linkadge, posted by SLS on April 20, 2009, at 8:58:31
>I guess my statements are merely opinions of >opinions.
I do apologize that I reacted >aggressively to one of your many attempts to >discredit me. You have done much worse in the >past, so I guess I should cut you some slack.
Attemtps?
My arguement is simply that there is no proof that *all* cases of depression are:
a) chronic
b) degenerative
c) associated with significant structural brain
alterations.If you read the specificity my my statement you will realize it is impossible to refute.
The studies you will find, will point to general *trends* but they are certainly not conclusive about the specific pathology of all depressive disorders.
The study you referenced also makes another sweeping claim that antidepressants "restore" the structural abnormalities in depression. This is unsubstantiated and quite possibly false.
To date there are only a handful of *preliminary* information that show that *some* antidepressants can improve *certain aspects* of brain structure in depression. The only one that comes to the top of my head is a study with paxil on PTSD patients.
Some antidepressants influence certain aspects of hippocampal neurogenesis. This is far from proving that antidepressants do infact reverse the strucal abnormalities associated with certain depressions. I think this is the hope, although there is insufficient evidence at this date to support the notion that this is actually the case.
Linkadge
poster:linkadge
thread:891025
URL: http://www.dr-bob.org/babble/20090416/msgs/891757.html