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Re: SSRI Induced Fatigue

Posted by SLS on April 11, 2009, at 6:57:56

In reply to SSRI Induced Fatigue, posted by chris87 on April 10, 2009, at 23:26:25

> I was originally taking Lexapro for anxiety and OCD, but it made me way too tired. I just recently switched to Zoloft, and I am having the same problem. I took Lexapro for over four months and the fatigue never subsided. Does anyone have any suggestions?
>
> I'm guessing that there are a few possibilities:
> 1. Add Wellbutrin
> 2. Add Modafinil/Provigil
> 3. Try a more stimulating SSRI (Prozac?)
>
> Could anyone give me the advantages/disadvantages of what I mentioned above? Are there any options that I am forgetting?

That's a logical set of alternatives. I would just suggest that perhaps adding the energizing TCA drug desipramine to an SSRI might offer some benefit. This strategy might be no better than the others, but it is something often used by some psychiatrists to produce a more robust antidepressant effect. However, the Wellbutrin + Zoloft (Welloft) combination is also popular. If the fatigue doesn't dissipate, you can try switching to Effexor.


- Scott

 

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