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Re: How come no MAOI/TCA poop out? Only SSRI poop » desolationrower

Posted by myco on April 4, 2009, at 11:23:26

In reply to Re: How come no MAOI/TCA poop out? Only SSRI poop, posted by desolationrower on April 4, 2009, at 1:50:08

Another idea I have about ssri's, and this is logical if you think about it, is the rate at which they come out.

You start on some med, under guidance of a dr who is inistant on ssri's and ignorant to the fact that dep is more than SE, and its working ok but not enough to "cover" everything you need it to do...then one day you have an issue or a problem that is "stronger" than the AD and it doesnt work aswell...then you change ssris because you complain to dr and they have heard of some new ssri that is supposed to do blah blah blah...and you enter the world of what i call "the ssri merry-go-round" switching all the time and getting no profound benefit from anything....because your issue is more than just SE...DA, NE, etc (i dont know everything involved in modern theory here) play roles to...hense maois being a good option as they hit all kinds of things. people on maois tend to stay or come back to maois...plus there are less to choose so if you have good experience on maois, better than ssris, you tend to stay in that area....and from someone looking inside from the outside...an ssri patient seeing a maoi patient doing "better for longer" you may get the wrong impression....ugh i think i just lost my argument there. blasted nardil lol

> i haven't heard any good ideas for why ssris are worse about poop-out. (and myco, always calling me in for the impossible questions...)
>
> but, lets says that NA has a more central regulatory role? NA drugs tend to do more normalizing on it, whereas 5ht tends to be merely raised?
>
> -d/r


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