Posted by myco on April 2, 2009, at 15:56:07
In reply to OCD and nootropics?, posted by g_g_g_unit on April 2, 2009, at 4:43:56
Have you experimented with the sup arginine? its a precursor of agmatine and involved in the polyamine oxidase system (i believe thats the right word)...has anxiolytic/Ad properties suggested in studies although still somewhat controversial.
N-acetyl cysteine is a great expectorant...I did notice I was happier on it but depressed somewhat the next day (dose dependant)...worked well on anxiety also it seemed (im anxiety patient)
I think mementine is a 5ht3 antagonist not sure about its role with glutamate though.
sorry not much help as of yet....still reading this topic. this sounds like a question for d/r
> just curious if anyone with OCD specifically (or any anxiety disorder really) has experimented with nootropics before? due to the suspected downregulation of ACH and dopamine systems by chronic SSRI use - and a general, persistent feeling of brain fogginess - i've been thinking of trying nootropics.
>
> some questions:
>
> 1) i'm currently being treated for undermethylation by a doctor's programme that involves the daily administration of l-methionine, p5p, magnesium/calcium, zinc and melatonin. it's advised that undermethylators avoid folic acid and choline supplementation. i was wondering therefore whether upregulating ACH via Galantamine, Huperzine A, Ginkgo, etc. is the same as taking pure choline? because my experiments with CDP choline indeed leave me feeling worse . . .
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> 2) is it generally advised that all OCD patients stay away from dopamine agents? or is it more of a grey-area issue, based on personal chemistry, etc. i ask because i currently have some Hydergine and Deprenyl at my disposal ..
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> 3) as far as I'm aware, the current agents - N-Acetyl-Cysteine, Memantine, etc. - being investigated for OCD therapy act by taming a hyperactive glutamate system. i assume then that it might be best to avoid something like piracetam, which effects the glutamate system? or is that wrong?
>
> thanks for your time,
> G
poster:myco
thread:888170
URL: http://www.dr-bob.org/babble/20090330/msgs/888249.html