Posted by myco on March 12, 2009, at 12:49:51
In reply to Re: On the use of CLONIDINE as a med AUGMENT., posted by desolationrower on March 12, 2009, at 3:57:56
d/r
I've read quite a few, well tons actually, of studies involving meds and mice/rats...dosages always seem massive. Like you mention...they don't translate like that into human doses. Do you have any idea, for future reference, how they extrapolate this data for patient usage (i.e. a formula or something for me)? It would help me make sense of tons of articles i've read and laughed at regarding the dose.
myco
> high doses of MAOIs are given because if you are doing an acute study you still need to inhibit all of the MAO that is in the body
>
> also you have to convert rat metabolic rate to human, higher doses /kg are needed for smaller animals
>
> -d/r
poster:myco
thread:884892
URL: http://www.dr-bob.org/babble/20090304/msgs/885034.html