Posted by iforgotmypassword on February 19, 2009, at 15:43:39
In reply to holy moly. i need to research tandospirone more. (nm), posted by iforgotmypassword on February 19, 2009, at 15:21:51
umm... holy f***, this seems like exactly what i need:
Paroxetine-Induced Bruxism Effectively Treated With Tandospirone
http://neuro.psychiatryonline.org/cgi/content/full/19/1/90
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Successful treatment of blepharospasm with tandospirone, a 5-HT1A partial agonist: a case report.
http://www.ncbi.nlm.nih.gov/pubmed/17987656
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Use of a serotonin 1A receptor agonist to treat restless legs syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/17110833
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then there's the stuff on how tandospirone improves cognition is schizophrenia, but buspirone does not. i'm not sure what accounts for this, probably something other than D2 occupancy (D2 blockade is likely already pretty heavy in those pts), maybe where they stand on the line in between antagonist to full agonist causes different response. while i do not have schizophrenia, i always wonder if my cognitive problems and deadened are serotonin related, this drug may be a purer and clearer way of testing this mechanism than buspirone, not to mention due to the fact that i can probably increase the dose to a higher level without worrying about D2.
there's probably more article wise. this is the first tandospirone specific search i have done, and i only went as far as the second page of results.
i may be able to convince my doctor to send in a request to the Special Access Programme for this. my currently existing extrapyramidal problems are reason enough to explain how buspirone could be unsuitable if he is asked. (amisulpride was a cinch when he tried to get it for me, but when he tried to get reboxetine for someone else, he was asked a huge amount of questions by pfizer (probably predicably, given that they would rather try to sell you drugs they already have in that market))
poster:iforgotmypassword
thread:881096
URL: http://www.dr-bob.org/babble/20090213/msgs/881130.html