Posted by jms600 on February 1, 2009, at 14:23:06
In reply to Re: Depersonalization and Effexor..., posted by linkadge on February 1, 2009, at 12:36:50
An article on Wikipedia noted that naltrexone had be used with some success (although I don't have a hope in hell of being prescribed that)!
Apparently SSRIs bought about some improvement but only by reducing associated anxiety and depression.
Clomipramine also bought about significant improvement.
I'm starting Efexor tomorrow so maybe I'll find some relief from that (in some form or another).
> >Do you have evidence that there is no evidence?
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> Yes, but not off the top of my head. I did a small paper on depersonalization disorder a few years back for school. Basically, from what I was able to find, research has not found SSRI's to be particularly effective for depersonalization disorder. There were some reports of anticonvulsants (ie tegretol) showing more sucess (although lamotrigne faired poorly in a study for depersonalization) and some doctors claiming sucess with AP's or opiate antagonists.
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> It could be totally different when depresonalization is a symptom of another.
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> I'm not telling you not to search the literature, but from what I recall, a few years back, the data was conflicting on the efficacy of AD's in depresonalization.
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> - Well, to be honest there is conflicting evidence of the efficacy of AD's in depression too, so I guess you just need determine what kind of evidence you are looking for.
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> Linkadge
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poster:jms600
thread:877364
URL: http://www.dr-bob.org/babble/20090104/msgs/877530.html