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Re: Marplan is GREAT!

Posted by SLS on January 17, 2009, at 20:03:06

In reply to Re: Marplan is GREAT!, posted by diego on January 17, 2009, at 18:38:26

> I wonder if ipronaizid is still available. It was the first AD, and the first MAOI. Started out life as an anti-tubercular drug, IIRC.

Iproniazid (Marsilid) was removed from the market because of hepatotoxicity. Isocarboxazid (Marplan) and phenelzine (Nardil) were introduced in 1959 and replaced iproniazid as an antidepressant. In the meantime, imipramine had been developed and tested in 1957 and also hit the market in 1959.


- Scott

 

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URL: http://www.dr-bob.org/babble/20090104/msgs/874586.html