Posted by desolationrower on January 9, 2009, at 1:08:43
In reply to Re: How to decrease NE ?, posted by SLS on January 2, 2009, at 7:05:13
> I forgot to mention that clonidine seems to be specific for certain areas of the brain. It binds to a subtype of NE-alpha that is expressed in the vasomotor center in the brainstem. This is how the drug works to reduce sympathetic tone and thus reduce blood pressure and heart rate peripherally. I don't know anything more about clonidine to know if it would be ideal for accomplishing your goal. My guess is that it wouldn't.
>
>
> - Scottheh ok i pretty much typed up the same post you made next before i realized you made me delete it. want to mention thought that peripheral effects are partly due to clonidine's effect on imadolazine (sp?) receptors. interestingly MAO is the enogenous agonist for imz2 i think, although i haven't figured out any relevence for that.
-d/r
poster:desolationrower
thread:871750
URL: http://www.dr-bob.org/babble/20090104/msgs/872906.html