Posted by SLS on December 21, 2008, at 14:10:00
In reply to Re: Agomelatin: could 5HT(2c) action be bad for sl » SLS, posted by Marty on December 21, 2008, at 13:10:35
Hi Marty.
Thanks for your input.
It was not a trick question! ;-)
I genuinely wanted to know your thoughts on the matter as it seems you are more knowledgeable than me in this area. I am amazed how accurate your appraisal is regarding dopamine function. I am extremely happy that you are feeling so well. I am very impressed with the intellect you demonstrated by actually designing your own successful treatment regime based upon combining drugs with complementary properties.
BRILLIANT!!!
My motivation for asking the question is that there has existed for many, many years a drug called ritanserin. It is a selective 5-HT2a/b/c antagonist that has shown itself to promote DA neurotransmission. Off patent, no drug compnay is interested in developing it for marketing. However, ritanserin is the paradigm agent for assaying 5-HT2 function and is used as a biological probe around the world.
- Scott
poster:SLS
thread:869924
URL: http://www.dr-bob.org/babble/20081214/msgs/870083.html