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Re: Abilify seems to have a 'brightning' effect.

Posted by SLS on December 20, 2008, at 11:31:31

In reply to Abilify seems to have a 'brightning' effect., posted by Jakeo29 on December 20, 2008, at 11:02:12

> ...stay tuned.

Will do!

:-)

I am glad to hear that Abilify is doing for you what it did for me when I first started taking it. I experienced small, but significant increases in both energy and motivation.

I take Abilify 20mg. I find anything below 10mg to be without much effect. I am beginning to think that there are less behavioral side effects at 10mg and above than there are at 2-5mg. Now that I have found 3 other drugs to combine it with, I find that I need Abilify to make everything else work such as I am experiencing a robust improvement from them. I tried discontinuing the Abilify awhile ago. I relapsed. I restarted it and felt fine. Abilify is what some people classify as a dopamine system stabilizer (DSS). It is unique among the marketed APs. It is the only one that produces both agonistic and antagonist effects at dopamine postsynaptic receptors. The drug's behavior changes as dopamine concentrations fluctuate. Technically, the term for this property is "partial agonist".

Two new DSS drugs are being developed and are in Phase III of investigation: asenapine and bifeprunox.


- Scott

 

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poster:SLS thread:869829
URL: http://www.dr-bob.org/babble/20081214/msgs/869834.html