Posted by NewQuestions on December 9, 2008, at 15:29:32
In reply to Strange shift in 5HT tolerances, posted by zzz7 on December 6, 2008, at 13:51:54
I read this in an article about SSRI's and the thyroid:
"Theoretically, an excess serotonin may lead to the opposite reaction. For example, excess serotonin leads to reduction in dopamine production, which then leads to increased norepinephrine production, leading to an increased stress response and cortisol production."
Could this be what is happening? Take an SSRI, it increases serotonin, which decreases dopamine (leading to depression/lethargy) and/or increases norepinephrine (increasing anxiety)? If so, it would seem one would need to take multiple drugs that specifically target these effects by increasing the dopamine and/or decreasing the norepinephrine? My understanding is that the new drug Abilify works with SSRI's and increases dopamine, but I am no expert.
poster:NewQuestions
thread:867043
URL: http://www.dr-bob.org/babble/20081204/msgs/867751.html