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I noticed something with the name brand, too » Neverquit

Posted by Racer on November 15, 2008, at 21:20:13

In reply to Success Story-surprise result, posted by Neverquit on November 15, 2008, at 16:16:13

Only in my case, I noticed that the allergic reaction I had to the generic went away! Kinda hard to miss, since the hives all over my face and chest were not inconspicuous...

(And I'll mention, it was only that one generic -- other generic fluoxetines haven't done that.)

In theory, the generics must be within 10% bioequivalent to the name brands, which in practice may mean that one generic may vary up to 20% from another. BUT, since those bioequivalance tests are done in vitro, who knows the actual absorption in vivo? The fillers may somehow interfere with absorption, or something else equally unexpected. (Maybe some of those inert fillers or binders are actually depressogenic?)

So, one possibility is that another generic would work for you, if the cost of the name brand is a problem. That's how my doctor solved the problem, once I had that reaction. The name brand didn't give me hives, so he wrote the scrip for capsule only and no hives.

On the other hand, it didn't work for me, but that's an entirely different matter...

(And I totally forgot to congratulate you! Yippee!)


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poster:Racer thread:863245
URL: http://www.dr-bob.org/babble/20081114/msgs/863283.html