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Re: Suppose you have unipolar depression -- » NKP

Posted by azalea on November 12, 2008, at 22:27:04

In reply to Re: Suppose you have unipolar depression --, posted by NKP on November 12, 2008, at 2:20:05

Sounds like stopping the lamotrigine caused a turn for the worse. While the rash is concerning, perhaps an option would be to retry lamotrigine, but start at a lower dose and titrate more slowly this time. Dr. Phelps (psychiatrist in Oregon and creator of psycheducation.org) recommends starting at 12.5mg lamotrigine and increasing by 12.5mg weekly. This is more conservative than the manufacturer recommendation. He has noticed a decrease in rash incidence with the more gradual titration.

> After she left the clinic, there was a dramatic improvement for a few weeks, but these last few days (especially since dropping the lamotrigine) it seems she is getting worse, not better. Considering her history, this is of great concern for me.
>
> Any thoughts?
>
> Thanks.


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poster:azalea thread:862336
URL: http://www.dr-bob.org/babble/20081106/msgs/862710.html