Posted by bleauberry on October 30, 2008, at 20:09:49
In reply to Luvox sadness, posted by pedrito on October 29, 2008, at 13:48:50
All antidepressants do that to me. Reuptake inhibition has not been a friendly mechanism for me. I have two theories why.
One is that while it is assumed the lag time for an antidepressant to work is when the receptors stop firing when the antidepressant initially increases neurotransmitter levels, but that in a few weeks they get accustomed to it and resume normal firing. My theory is that for many people, that resumption of firing never happens. All that serotonin throws dopamine and norepinephrine way out of balance and the person feels worse in several ways. The same ways you described.
Another theory is that the depression is not caused at all by low neurotransmitters. It is something else. Hormones for example. Low cortisol equals depression. Low thyroid equals depression. Not low according to some predetermined wide range on a lab sheet, but low for that particular person's unique genes. When those hormones are adjusted in the correct direction, it generally does not feel good in the beginning. It takes time for adrenals and thyroid to readjust, and in the meantime it feels bad. Well, all the antidepressants in one way or another impact the hormones.
Those momentary hints of goodness you experience could be signs of good things to come. But if they become more infrequent or disappear, well, I would throw in the towel. Actually, whenever a med makes me feel like crying when I didn't feel that way to begin with, I don't waste any time ditching it. It is obviously a wrong med for me. Someone else can play brave guinea pig and give it more time, but I have a job and family and bills. Even in my normal depressed state, I can function better than on antidepressants that make me feel worse. I don't need to be crippled more than I was. I don't question why the med made me feel bad, I just know it did, and since I am my body's best boss, I said enough is enough. There is no shortage of other options to try.
poster:bleauberry
thread:859741
URL: http://www.dr-bob.org/babble/20081027/msgs/859986.html