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Re: Vicodin ~someone please explain to me why.... » jaclinhyde

Posted by seldomseen on October 4, 2008, at 11:45:08

In reply to Re: Vicodin ~someone please explain to me why...., posted by jaclinhyde on October 3, 2008, at 12:18:31

"Endogenous opioid tone" is a clinical term that describes the level of circulating natural opiate peptides that circulate in all of us.

You may have heard of endorphins. These are part of the factors that make up endogenous opioid tone.

There is some evidence that suggests that people with depression have low endogenous opioid tone that contributes to the condition.

I would suggest that you have a rational talk with your pdoc about your response to the Vicodin. It could be very clinically significant and give him/her a springboard from which to try a new treatment. This is of course assuming that he/she won't prescribe an opiate for you.

Have you considered tramadol (ultram) or potentially Effexor?

http://www.ncbi.nlm.nih.gov/pubmed/18364623?ordinalpos=11&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

On a side note, I'm not a big fan of Vicodin or percocet, but not because of the opiate. These drugs also contain acetaminophen, which is IMO one of the most dangerous drugs available OTC.

Seldom

 

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