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Re: Circadin - Lundbeck launches new melatnonin tablet » Bob

Posted by Marty on September 25, 2008, at 15:45:17

In reply to Re: Circadin - Lundbeck launches new melatnonin tablet » linkadge, posted by Bob on September 24, 2008, at 22:20:07

> The interesting thing is the rumors that Voldoxan is more effective than the SSRI's. It seems like the melatonin actions might have something to do with that? Maybe melatonin in combination with the serotonin action?
---
Hi Bob,

The 5-HT 2b/2c receptors antagonistic action of Agomelatine doesn't 'increase' synaptic serotonin like SSRI. In fact, this action reinforces frontocortical adrenergic and dopaminergic transmission. Isn't fascinating ? :)


/\/\arty

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URL: http://www.dr-bob.org/babble/20080915/msgs/854051.html