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Re: N-acetylcysteine and bipolar depression » chiron

Posted by SLS on September 20, 2008, at 8:24:00

In reply to Re: N-acetylcysteine and bipolar depression, posted by chiron on September 20, 2008, at 1:23:44

> My pdoc suggested it:
> am: 600mg 2-3
> pm: 600mg 2-3
> This looks like a lot, but I guess they did studies for schizophrenia up to 6000mg a day.
> btw - I take Lamictal, Wellbutrin, Celexa, Xanax, Synthroid.
> I haven't taken it very regularly and for very long to report on results.

Good luck. I hope to hear good things.

I don't know what kind of data was considered when establishing the study doages of NAC treatment for bipolar disorder. I doubt NAC has been studied in such a fashion as to determine a therapeutic range appropriate for treatment of mood disorders.

Theoretically, one would not want to take too much NAC, as it might prevent apoptosis (cell death) of cancer cells. If you do respond to 2400mg per day, a dosage not much higher than that used in the Berk study, you might at some point want to adjust the dosage downward to establish the minimum effective dosage for you.


- Scott

 

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