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Re: Psychiatric Drug Chart? » theo

Posted by SLS on September 1, 2008, at 13:00:47

In reply to Re: Psychiatric Drug Chart? » SLS, posted by theo on September 1, 2008, at 10:20:07

> Do you take Nortriptyline as a single dose at bedtime or morning?

You can take a single dose of nortriptyline before bed. Personally, I like to think that a more even blood level throughout the day makes sense. I take 50mg in the morning and 100mg before bed.

> Also, didn't see Deplin in your combo. Did you stop it? Honestly for me, I don't know if it's worth the extra $60.00/month.

I discontinued Deplin mainly because it was disturbing my sleep. I was having vivid nightmares and would end up throwing myself off the bed and onto the floor. I also would talk very loudly and yell occasionally. My neighbors are not too happy with me.

So far, I don't think I have suffered any deterioration in my depressive condition. If I go back to Deplin, I would take 1/2 pill a day (3.75mg).

If you are in doubt of whether Deplin is helping or not, you can simply discontinue it for a week or so. There is no need to titrate back to 7.5mg should you discover you still need Deplin in your treatment regime. I have become suspicious that the initial response to Deplin fades gradually over time such that it is unnoticeable.

Regarding NAC, I first had as a goal to use this substance to prevent and possibly reverse the cell death that comes with affective disorders, especially bipolar disorder. I wanted to take NAC as an antioxidant and anti-apoptotic. I then stumbled over a blinded study of NAC as a treatment for bipolar depression. The results of the study were that NAC after 8 weeks produced a significant reduction in depression scores. The study used 2000mg per day (1000mg b.i.d.). I am starting out at 1200mg and will move up to 1800mg if positive results aren't imminent.


- Scott

 

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