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will there be new meds...SNDRIs

Posted by B2chica on August 13, 2008, at 8:37:31

its a long time before they're out (if they come out)i'm sure but one is in clinical trials at least right now.

there are three new meds being worked on right now. a new Class of AD called SNDRI (serotonin, norepinephrine DOPAMINE reuptake inhibitors)...just what 'I' am looking for.

the three i found are called:
tesofensine (currently in clnical trials)
brasofensine (under development)
and
GlaxoSmithKline's NS2359 (under development)

however Tesofensine will most likely be marketed as a treatment for obesity (as reserached in phase II trials) now they are in phase III but it didn't say what for, if they've switched to look at potentially depression/bipolar or staying with appetite suppressant. it was originally researched for treatment of alzheimer's and parkinson's.

Brasofensine was researched for treatment of parkinson's and depression. the bad news is Phase II trials were conducted in 1996 and though was shown to be well tolerated the current status of this drug is unknown.

and i couldn't find any info on the GSK drug, so i don't know the status of this.

i'm writing about these meds incase anyone out there has more information about these meds.

i think the key to my issue is dopamine and if i could find a different drug that targets dopamine i'm thinking specificially D1 it could really help.

thanks
B2c


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poster:B2chica thread:845876
URL: http://www.dr-bob.org/babble/20080805/msgs/845876.html