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Re: Ambien hallucinations - Some thoughts » Amigan

Posted by yxibow on August 10, 2008, at 20:30:34

In reply to Re: Ambien hallucinations - Some thoughts, posted by Amigan on August 9, 2008, at 21:44:34

> I wonder if these "trips" resembles the trips from Amanita Muscaria mushrooms. Both are GABA agonists...
> On the other hand, Benzodiazepines are GABA agonists too, but they are not known to cause hallucinations to the majority of their users. Perhaps this shows us that dispite their similarities, Z's and Benzos have some important differences.


The differences is that pseudobenzodiazepines are targeted directly at the sleep subreceptor of GABA-A.

Benzodiazepine sleep agents are also targeted at the sleep subreceptor, but all benzodiazepines still have sedative-hypnotic (sleep), anxiolytic, amnesic, and anticonvulsive propertices.


The only question is how much of each they have -- Restoril and especially Halcion will have much more targeted at the sleep receptor, but they also will still have minor properties of each of the others I mentioned.


Anything that touches GABA-A will have the panoply of rare to moderate side effects that include sleepwalking, hallucinations, amnesia, etc.


-- Jay

 

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