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Re: N-Acetyl Cysteine (NAC) for bipolar depression » bleauberry

Posted by SLS on August 3, 2008, at 5:18:24

In reply to Re: N-Acetyl Cysteine (NAC) for bipolar depression » SLS, posted by bleauberry on August 2, 2008, at 19:42:17

Hi BB.

> Any theories as to how NAC works?

Yours look pretty good.

> To the best of my knowledge glutathione is the major player in detoxification of environmental or biological pollutants/toxins. I wonder if that is the mechanism by which it works...that is, removing toxins that are clogging receptors, messing up immune systems, messing up neurtransmitters, confusing genes, whatever. Or is there something else? Any ideas?

One other site at which glutathione uptake is important is in the mitochondria. Mitochondria cannot manufacture glutathione on their own, so they are dependent on the presence of glutathione in the cytosol. I have heard several theories regarding the etiology of depression implicating the mitochondria, so maybe there is something to it.


- Scott


 

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