Posted by Bob on August 1, 2008, at 12:13:45
In reply to Re: Let's try that again... food for thought., posted by satsumas on August 1, 2008, at 1:31:33
> but don't forget that that's what strong medicine and ECT are designed to do in some respects. all these downstream modifications are designed to change the expression of genes, probably via some sort of epigenetic pathway. and remember, he's looking at completed suicides -- obviously let's hope ( or perhaps not hope, I don't know what the correct sentiment is for these sad cases) that those who are being treated with effective doses of the right medications do not have the similar level of epigenetic changes.
>
> although definitely food for thought.
>
> anyone know which psychotropic meds or substances, of any class, do the most action (positive or negative) at the genome itself? solid doses of lithium seem to do something, right?
>
> any other meds remodel the genome or affect its expression thereof?
Yes, agreed, but I was kind of referring to a method which would more directly manipulate the genes I guess. A point at which we could cleanly affect individual genes without requiring a cascade of changes which eventually leads to a modification of gene expression way down the line.
poster:Bob
thread:843379
URL: http://www.dr-bob.org/babble/20080727/msgs/843477.html