Posted by Bob on July 23, 2008, at 13:43:44
Is anyone here familiar with the pros and cons of the various atypicals as an augmentation to antidepressants?
Here's what I think I know:
Abilify can be somewhat stimulating and there's evidence (quite anecdotal at this point) of a "dose threshold" beyond which the drug becomes more calming and sedating. This drug caused insomnia and anger for me. It seems to be more weight neutral than some of the others.
Zyprexa is more sedating, and is notorius for weight gain and risk of diabetes. I've heard this is the best drug for anti-suicidality, anti-anxiety, and may even offer some anti-obsessional benefits.
Risperdal I don't know much about. It seems to be somewhat depressogenic and sedating, but I've never taken more than one or two doses before quitting.
Geodon I know very little about also, other than it is probably the most stimulating. I once tried a single dose of the med years ago, and within a half hour had entered into an akathisic panic.
If anyone has other insights, I'd love to hear about them.
poster:Bob
thread:841617
URL: http://www.dr-bob.org/babble/20080718/msgs/841617.html