Posted by SLS on July 5, 2008, at 8:54:56
In reply to Re: Long term lithium » SLS, posted by linkadge on July 5, 2008, at 8:37:04
> Yes and a similar practice was used for *thereaputic* dosing with antipsychotics.
So what? Just because this method of determining dosage doesn't work for one class of drugs doesn't mean that it won't work for another.
By the way, I was very specific as to describing this method as it pertains to bipolar disorder.
> I think that if lower doses have documented effect in unipolar depression, then it known that lower doses do have an effect.
Unipolar: 300-600mg
Listen, I had the opportunity to titrate lithium using blood levels and the appearance of tremulousness both at the same time. They did indeed agree with one another in establishing a therapeutic level for BIPOLAR DISORDER. Pretty clever if you ask me. Some people will respond to 0.8 ng/ml. Others will need 1.2 ng/ml. The appearance of tremulousness seems to be related to an individual's responsivity, and helps place the person at the minimum dosage that will produce efficacy.
- Scott
poster:SLS
thread:837754
URL: http://www.dr-bob.org/babble/20080626/msgs/838146.html