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Re: Long term lithium linkadge

Posted by SLS on July 5, 2008, at 8:54:56

In reply to Re: Long term lithium SLS, posted by linkadge on July 5, 2008, at 8:37:04

> Yes and a similar practice was used for *thereaputic* dosing with antipsychotics.

So what? Just because this method of determining dosage doesn't work for one class of drugs doesn't mean that it won't work for another.

By the way, I was very specific as to describing this method as it pertains to bipolar disorder.

> I think that if lower doses have documented effect in unipolar depression, then it known that lower doses do have an effect.

Unipolar: 300-600mg

Listen, I had the opportunity to titrate lithium using blood levels and the appearance of tremulousness both at the same time. They did indeed agree with one another in establishing a therapeutic level for BIPOLAR DISORDER. Pretty clever if you ask me. Some people will respond to 0.8 ng/ml. Others will need 1.2 ng/ml. The appearance of tremulousness seems to be related to an individual's responsivity, and helps place the person at the minimum dosage that will produce efficacy.

- Scott




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