Posted by Molybdenum on June 24, 2008, at 21:25:16
In reply to Re: ok what to add to the cocktail effexor*Trazodo » Molybdenum, posted by Bob on June 24, 2008, at 16:04:16
> Is there any evidence of this "California Rocket Fuel" being effective with Cymbalta in place of Effexor?
Hi Bob,
Trouble is that the defacto bible on such matters - "Stephen M. Stahl - Essential Psychopharmacology 2nd edition", is printed in 2000. Cymbalta (Duloxetine) was not approved by the US FDA until 2004. So that's one reason why it might not be as popular as venlafaxine + mirtazapine.
Incidentally, I just read Wiki's blurb on Duloxetine at http://en.wikipedia.org/wiki/Duloxetine. It doesn't sound like a fantastic AD. In fact, Wiki's article really makes it sound like a pointless medication for treating depression. It apparently has some other uses. Maybe that's the justification for it's existence.
IMHO "if I were you" and I was feeling horribly depressed, I would want to feel better ASAP. So choosing a combination of drugs that commonly produces positive effects and that has been prescribed together for years would be my choice over something different or new. Assuming you don't have a problem with venlafaxine, why not go with the tried & true approach? It's not like Eli Lilly is going to pay you to run experiments on yourself.
We all think that newer = better, but it's often simply untrue.
So there's my 5c worth. ;)
Good Luck - I hope you're feeling better soon.
Mr. M.
poster:Molybdenum
thread:836131
URL: http://www.dr-bob.org/babble/20080617/msgs/836299.html