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Can High SSRI doses cause Long Term Anxiety ?

Posted by Mike_Cohen_2 on June 24, 2008, at 16:56:03

As I've stated in recent posts, my anxiety has been my big problem since my brother past away 15 mos. ago.

I was on Serzone prior to his death for periodic Panic Attacks, but no generalized anxiety. Had trouble getting on an SSRI as I started getting crazy anxiety and the Serzone wasn't cutting it even at high doses. Had trouble combining Serzone with SSRI, so several mos. passed before I was able to get on Lexapro. My doc. took me up to 30mg over a few weeks, but anxiety persisted, then we made the switch to Zoloft 100mg. She tinkered with mood stabilizers and other augmenting agents, but nothing helped the anxiety. Recently, I said to myself, "I think these meds make me feel worse". I think I'm gonna try and get off everything but the benzos as they seem to work the best. The last drug I stopped was the Lamictal as it didn't do anything for me. It was only given for suspected BP II, I still don't know about that one.

So here is the deal. I cut my Zoloft to 75mg today from 100mg, and I feel a great reduction in my anxiety. It's still there, but I'd say it's about 30% better today, which is huge for me. My head is clear, I actually laughed with my kids today and was able to focus on them and no so much myself. You guys don't know me, but for the past 15 mos. I've been so caught up in this crap and constantly asking myself how I'm feeling all day long, checking my pulse, etc.

So, I ask this question and if the answer is yes, can I get some supportive reasons why too high of a dose of an SSRI can make anxiety worse ?

All along, my pdoc has been saying more is better for me due to my symptoms, but I'm just going off of my experience today which would seem to dismiss her statement. Thanks in advance as always.........

Gary


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