Posted by yxibow on June 17, 2008, at 14:51:23
In reply to Serzone and Trazodone?, posted by anthonyg23 on June 14, 2008, at 12:37:59
> Hey guys,
>
> The ONLY medication that has EVER worked for me has been Serzone. It changed my life in ways I can't even describe. I was anxiety free...instead of the first thought about any topic coming to my head being negative, it would be positive. My attitude was completely different, I was incredibly happy and the outlook on life was positive.
>
> I've tried so many AD's and none work even close to this drug. Does anyone know of anything the is even closely similar in effect to this drug??? Also, I've read a lot about Trazodone as an AD (similar chemical structure)...Would it be worth trying this AD (even though it's used as a sleep-aid more now) to see if it gives me similar effects as the Serzone??
>
> Steven
If you can get used to the horse tranquilizer effect that Trazodone has at high doses for adults who need antidepressant effects, then its for you. I doubt most people can sit through that and operate heavy machinery possibly.Also Trazodone has a peculiar metabolite mCPP, which normally is not harmful to most people, but can deepen psychosis if its latent or present.
It also carries the risk of priapism (unwanted erection), which I have gotten around of twice in a hilarious but humour I won't repeat here again. True priapisms are hospital cases.
Also you -cannot- take any alcohol while adjusting to Trazodone. It can cause a blackout -- at least for me when I thought I had eliminated everything and then took the Trazdone for night and ended up on the bathroom floor.Anyhow, long story short, if a particular agent is -working- for you then why stop?
The makers of nefazodone (Serzone) fled the liver reports because of deep money assets but generics of course are out there.
What I would suggest is having a liver test at least twice a year if not more -- the ALT (and I think there may be one more), to see what is going on.
If nothing is happening, continue, but remember that everything else you take will also affect the liver, so go easy on NSAIDs (ibuprofen) if possible, and definitely alcohol if possible too.
-- jay
poster:yxibow
thread:834597
URL: http://www.dr-bob.org/babble/20080617/msgs/835093.html