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Re: Best treatment for MAOI hypertensive crisis?

Posted by undopaminergic on June 14, 2008, at 8:52:09

In reply to Re: Best treatment for MAOI hypertensive crisis?, posted by SLS on June 8, 2008, at 11:36:29

> Some people like using Thorazine as an antidote.

I haven't heard of Thorazine being exploited for its hypotensive effects, but rather as an antidote to serotonin syndrome (although cyproheptadine would be preferred unless intravenous administration is needed).

Nifedipine (Procardia) seems to be the most popular choice by far for MAOI-associated hypertensive attacks. I would expect nitroglycerin to act more quickly, however, as it's very rapidly absorbed through mucous membranes (usually sublingual).




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