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Re: Linkadge?

Posted by linkadge on June 5, 2008, at 19:00:02

In reply to Re: Linkadge? » linkadge, posted by johnj on June 5, 2008, at 12:21:52

This study seems to suggest that both mirapex and venlafaxine have some ability to increase gaba levels in the prefronal cortex.

http://cat.inist.fr/?aModele=afficheN&cpsidt=17217135

Here's some study of the effect of hallucinogenic 5-ht2a/c agonists on the prefrontal levels of gaba.

http://www.nature.com/npp/journal/v20/n1/abs/1395229a.html

There is some evidence that anticholinergic substances can reduce the release of glutamate in the prefrontal cortex. In some models of depression, acetylcholine levels are elevated in the prefrontal cortex leading to prefrontal hyperactivity. In these cases anitcholinergic drugs may reduce activity (ie benadryl, scopolamine etc).

Taurine increases the levels of GAD (which increases GABA synthesis). It also interacts directly with gaba receptors to produce inhibition.

As far as the ginger root goes, it has a nonsedating gabergic effect. It is also a mild MAOI which may decrease prefrontal hyperativity.

Linkadge



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