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Re: Parnate and Suboxone?

Posted by undopaminergic on May 28, 2008, at 6:25:47

In reply to Parnate and Suboxone?, posted by okydoky on May 27, 2008, at 18:46:32

> CAn this be done? Selegiline with Sub...? Parnate with oxycontin? I thought this was okay but now I read on another site that perhpas not?
>

Most opioids can be used with MAOIs. However, tramadol, pethidine (meperidine), and possibly high doses of propoxyphene and methadone, can interact with MAOIs to produce serotin syndrome. However, some people have used tramadol with MAOIs without significant hyperserotonergia, so even those combinations may be safe if they are initiated with caution - that is, starting with very low doses.


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