Posted by SLS on May 28, 2008, at 5:28:48
In reply to Re: Clonidine Contributing to Depression? » SLS, posted by ace on May 28, 2008, at 0:33:03
> I personally just don't like to discount any drug as a possible treatment, especially when dealing with refractory illness.
Yes, sir. Definitely.
> > What was the case profile of these folks. Does anything stick out in your mind as a commonality among individuals with depression whom respond favorably to clonidine?
> Very much so- the vast majority were diagnosed with ADHD or ADHD type symptoms. Although I have seen anecdotes on 'normal' depression (without co-morbidity) responding to it favourably. I believe I have some on trials on it too- for OCD, ADHD- always with depression as a co-morbid problem.
The ADHD I knew about. Not the OCD. Interesting. I guess that makes sense if NE pathways to the frontal cortex are overactive.
> > Of course. However, I do not believe that inprecision is a de facto property of psychopharmacological treatment.
> At this point in time I would think it so. What would suggest otherwise to you at the present?
I don't think we are that far away from using microarray techniques to assess gene activity. Pinpointing which genes are over- or under- expressed might allow for the selection of specific drugs to an individual.
About choosing medicine as a profession, you would not be the only physician to have a mental illness. I guess if Kay Redfield Jamison can do it, so can you.
http://en.wikipedia.org/wiki/Kay_Redfield_Jamison
Good luck.
- Scott
poster:SLS
thread:829199
URL: http://www.dr-bob.org/babble/20080528/msgs/831567.html