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Re: The best Tricyclic for anxiety....

Posted by linkadge on May 27, 2008, at 19:37:13

In reply to Re: The best Tricyclic for anxiety...., posted by SLS on May 27, 2008, at 17:32:18

I would think doxapin, elavil or clomipramine would be better than imipramine for GAD. These two have antagonist effect at 5-ht2a/c, 5-ht3 which imipramine does not have. I think imipramine is the most studied in this regard but that does not necessarily equate to efficacy.

If sleep disturbance and/or GI problems are prominant, this might be another reason to choose elavil or doxapin which have antihistamine effects too.


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URL: http://www.dr-bob.org/babble/20080519/msgs/831489.html