Posted by SLS on May 21, 2008, at 8:01:06
In reply to Re: Pergolide for Bipolar. @ SLS, your comments pl, posted by garylee on May 17, 2008, at 12:48:42
Undopaminergic is exactly right.
Pergolide and cabergoline are both agonists of the 5-HT 2B receptor. This is probably the mechanism by which cardiac valvulopathy develops. From what I've seen, cabergoline is thought to be more apt to produce this side effect than is pergolide. I'm not sure this is true, though. As Undopaminergic said, you should stay away from both of these drugs.
Mirapex and Requip seem to be safe with regard to valvulopathy.
- Scott
poster:SLS
thread:829642
URL: http://www.dr-bob.org/babble/20080519/msgs/830289.html