Posted by bleauberry on March 28, 2008, at 18:28:39
In reply to Happy Ending :P - OCD/major depression/psychosis, posted by temoigneur on March 28, 2008, at 0:51:37
I have often thought Memantine might have some unknown potential in psychiatry. There is evidence that it prevents or reverses tolerance to opioids and stimulants. I sometimes wondered, if someone's own receptors are so tolerant of natural dopamine that the receptors don't work and leave the person depressed, maybe memantine could reverse that to normal? Purely hypothetical, but something I have pondered over the years. The thing is, there was one case study done where a small group of depressed patients were given Memantine and not a single one of them got any benefit. So I think research and interest just isn't there. But still, there is some nagging suspicion deep within me this drug holds more promise than anyone knows. Anything that has even a hint of potential at reversing tolerance deserves some serious attention.
You are proof of that. I love your post. I have no idea how they ended up choosing Memantine for you or what the reasoning was, but I'm sure glad they did.
poster:bleauberry
thread:820264
URL: http://www.dr-bob.org/babble/20080316/msgs/820388.html