Posted by bulldog2 on March 28, 2008, at 15:24:33
In reply to Re: Just Started Strattera For ADHD, posted by undopaminergic on March 27, 2008, at 22:05:06
> I'm somewhat amazed to see that some people have had a positive experience with Strattera.
>
> I tried 40 mg for a week (only a week, as it's darned expensive here in comparison with the alternatives, and also because I was skeptical).
>
> It didn't do anything but cause some minor side effects, raising the heart rate (possibly the blood pressure too) and producing a shivering / hair-raising tendency.
>
> Basically the same was true in a previous, more than 4-week long, experience with reboxetine, another selective noradrenaline reuptake inhibitor (SNRI). After months without SNRIs, I tried adding reboxetine to selegiline, and found the previously described side-effects exacerbated considerably, but additionally noted also coldness of the extremities, feelings of exhaustion, and drowsiness - I almost fell asleep while driving. The experiment was repeated later with the same results.
>
> Additional effects noted during the initial trial with reboxetine were a tendency to emotional blunting and depersonalisation. It put an end to a syndrome of depressive feelings, including suicidal ideation, oversensitivity, and agitability - symptoms that haven't returned years after cessation of reboxetine. While that effect was most welcome at the time, it may not be welcomed by everyone. I've seen complaints from others of similar - or even more intense - experience with reboxetine.I think the problem with ssri's or snri's is the strong reuptake of only one neurotransmitter. If one's problem is the imbalence of only ne or se you may get great results but I have a feeling that is a minority of ppl. To this day maois and tca's work better for atypical depression or major depression than these newer drugs. They also work on both ne and se and in the case of maois also da.
poster:bulldog2
thread:819688
URL: http://www.dr-bob.org/babble/20080316/msgs/820360.html