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Re:Prozac Vs. Effexor SSRI's }}}Shenandoah and » jms600

Posted by Jay_Bravest_Face on February 18, 2008, at 14:10:19

In reply to Re: Prozac vs Effexor, posted by jms600 on February 17, 2008, at 16:30:36

> I have read on here recently that going back onto an SSRI after a long break can achieve the same antidepressant effect the patient got when he/she first went on the drug.
>
> Not sure how this works or why - perhaps it has something to do with the brain becoming almost 'tolerant' to the drug, and so going back onto it after a break can 'reset' things (if you know what I mean)? Some of the other posters on here are far more knowledgeable about all this than me so maybe they could advise..?
>
>
>

I don't know...I have tried this, and found it of no value whatsoever. In fact, in the book "Noonday Demon" the author strongly urges against this. Going back and forth constantly between medications on a rotating basis does not seem healthy.

I think the best bet is to get the SNRI effect going. So, you want to look at:

a)switching to meds like Effexor, Cymbalta
b) combo of SSRI + Stimulant
c) tricyclic + SSRI
d) possible combo of SSRI + Wellbutrin
e) if you can afford weight gain, add Remeron

Anyhow, just IMHO, but I unfortunately waited too long in between meds and gave away years accepting that I just had to live "sub-satisfactorily" with just an SSRI.

Best,
Jay



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