Posted by linkadge on December 12, 2007, at 22:27:58
In worms at least.
Apparently, the effects of the drugs mimic the effects of caloric restriction, through modulation of 5-ht2 receptors.
From what I understand, the drugs turn on the same genes that makes the worm think it is in a starving mode. I am assuming the worm is fed the same amount of food, even if its appetite is increased by the drug. I would also assume that this effect would be counteracted if an increased number of calories were consumed.
Anyhow, see what you can make of it.
Linkadge
poster:linkadge
thread:800469
URL: http://www.dr-bob.org/babble/20071204/msgs/800469.html