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Re: placebo vs. antidepressant Larry Hoover

Posted by linkadge on September 13, 2007, at 16:43:33

In reply to placebo vs. antidepressant, posted by Larry Hoover on September 13, 2007, at 13:51:57

>If these statements were true, what would we >find when we looked at the placebo-controlled >clinical trial data?

We might find analysis like this:

http://www.vaccinationnews.com/DailyNews/June2002/CanPlacebo25.htm

In a soon to be published study, Dr. Arif Khan, a psychiatrist at the Northwest Clinical Research Center in Washington, analyzed the Food and Drug Administration's database of 52 clinical trials in depression, involving nine new antidepressants, conducted from 1985 to 2000. ***Since the agency requires drug companies to report all data from all studies for drugs under development, the database can give a more accurate picture of a new drug's efficacy than the medical journals***, where positive findings are far more likely to be reported than negative ones.

Dr. Khan found that in only 48 percent of the 52 clinical trials was the antidepressant superior to the placebo.

Linkadge


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URL: http://www.dr-bob.org/babble/20070911/msgs/782711.html