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Re: Effexor/Cymbalta combo » grumpii

Posted by CareBear04 on August 30, 2007, at 22:11:40

In reply to Effexor/Cymbalta combo, posted by grumpii on August 28, 2007, at 11:29:08

Like everyone else, I would recommend just one of the combo since they essentially work on the same neuroreceptors. In my experience, Cymbalta was much more effective for me than Effexor. I took 150mg of Effexor XR for about six months, but maybe that wasn't a high enough dose to get the norepinephrine effect. On the other hand, I felt the full effect of Cymbalta at 60mg a day. I've been on countless combos of serotonergic meds without disaster, and I think Serotonin Syndrome might be a zebra-type scare.

Doctors that I've talked to have spoken highly about Cymbalta's effect on chronic pain. Since depression and migraine are comorbid and being depressed can make you more susceptible to migraines, I would suggest whatever regimen best treats your mood problems. As for migraine prophylaxis, have you tried aspirin? I know it's probably the most basic treatment out there, but since platelets activate and aggregate more readily in migraineurs and aspirin inhibits platelet function, some people find it very effective. But as for Effexor AND Cymbalta, I would stick with one.

CB


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