Posted by barbaracat on August 12, 2007, at 15:50:51
In reply to Re: Tolerance to Benzo Anxiety Effects » boveni3, posted by Quintal on August 11, 2007, at 21:36:53
I've noticed a progressive tolerance building up now that I've been taking benzos more frequently because of some stresses. I take clonazepam and lorazepam, interchanging them. It's getting to where I could easily take a small handful and hardly feel it.
This has happened periodically and I'll usually ramp down on the doses. I usually find no withdrawal problems, but I never just discontinue, only reduce slowly.
I find that gabapentin will help in these situations. It binds to the GABA receptors differently and even though it has a very short tolerance life, the action seems different and I can at least get some relief when benzos have pooped.
What I'm searching for now is a way to replenish the GABA naturally and have been trying various aminos and herbs. Amino GABA doesn't do squat since it doesn't cross the bbb, but L-theanine, an amino acid, may be a contender. Another is rosavin, a high mountain flower which strengthens the adrenals and lifts the mood. I order Ameriden brand over the net.
One thing that's become clear is the importance of Omega 3's and 6's, fish oil, flax oil and evening primrose oils for example. These keep the fatty surfaces of the cell membranes fluid and permeable so the neurons can do their work of receiving and releasing molecules in a more healthy state.
- BarbCat
poster:barbaracat
thread:626479
URL: http://www.dr-bob.org/babble/20070808/msgs/775781.html