Posted by edgaras on August 2, 2007, at 21:01:36
In reply to Re: Zanaflex follow up - sustained release, posted by JohnX2 on December 10, 2001, at 15:32:14
Just got 2 mg pills for my jaw pain. Will see what happens. Starting off with 1 mg. It appears that my jaw pain is related to TMJ problem, more of a structural and anatomic problem with alignment of the joint. MRI/CT is showing degeneration of condyle head, with possible cyst in the area as well. I'm sure there is psychosomatic component as well - anxiety might cause increase in pain so will see what happens.
There was some discussion on clonidine, so to add my 2 cents, clonidine is used for hypertension, and has much higher potency (doses of .1 mg).
Interestingly, another "muscle relaxer" cyclobenzaprine has totalally different mechanism. It "binds to the serotonin receptor and is considered a 5-HT2 receptor antagonist that reduces muscle tone by decreasing the activity of descending serotonergic neurons." In contrast to hypotensive clonidine and zanaflex, this drug has been shown to "increase heart rate in animals".
I tried cyclobenzaprine and all it did was produce
drowsiness. I remember leaving the stove on and falling asleep to wake up to room full of smoke. Not good idea to start cooking on muscle relaxers.
From what I remember, it didn't do much for pain.
poster:edgaras
thread:85853
URL: http://www.dr-bob.org/babble/20070730/msgs/773629.html