Posted by dewdropinn on July 24, 2007, at 0:20:04
In reply to Re: Patch decision - What to do?, posted by JohnSky on July 23, 2007, at 15:21:26
The dietary issues are largely theoretical. Bristol-Meyers worked very hard to induce tyramine reactions during initial clinical studies without any luck. They have lobbied with the FDA to get the black box warning removed, because all of their research suggests that the dietary precautions are unnecessary. The dietary risks are miniscule at best, but they are worth knowing about because of the severity of the possible side effect. Does this make sense?
Raising the dose may prove beneficial -- it made a huge difference for me. If bipolarity is an issue, it may make sense to try reducing the dose -- you can easily cut the patch and assess your response -- this would seem to be the most readily testable option. I wish that I could give you more definitive direction. Best of luck, and please let me know how everything goes.
Drew
> Thank you for the idea about going up to 9mg. At that dose I believe the dietary constraints come into play? That is the strategy I may need to go.
>
> I need to do something as I feel anxious and my mood is down. Over the last few days I just feel tired and "strange". Sort of a "out of touch feeling". This may be from feeling anxious alot of the time from the medication. Or from being over-medicated as I am also on Lithium and Seroquel. I just feel scared and that the EMSAM is making me worse. I have been on it 24 days. I will give it until Wednesday and then discontinue if I still feel so out of sorts.
>
> John
poster:dewdropinn
thread:769334
URL: http://www.dr-bob.org/babble/20070719/msgs/771547.html