Posted by Jedi on June 4, 2007, at 14:44:26
In reply to Re: Im thinking the pdoc will do this ..., posted by UgottaHaveHope on June 1, 2007, at 2:40:55
> 15mg for two days, 30mg for three, and then 45 from there out.
>
> Ive been gone for a month. Why did you go off Nardil? MichaelHi Michael,
I've been gone for a time also. I decided to try Parnate because of the sweet carbohydrate cravings and associated weight gain from Nardil.I'm afraid I may have to return to Nardil because of some spontaneous blood pressure increases on Parnate. This happens with some people. I've woken in the middle of the night with just a splitting headache, and I'm the person that does not get headaches. I thought it might have been a sinus infection, but I don't even get bad headaches from these. I went to the clinic to get some antibiotics for the sinus infection and they measured my BP at 160/100. So I've cut my Parnate in half, down to 40mg and haven't had any more headaches, and the BP is averaging about 130/75. But I don't know if 40mg of Parnate will hold off the major depression. I've reconciled myself to dysthymia, I can at least function with this. I have to E-Mail my MD and get permission for all of this. Then I have an appointment with him in a couple of weeks and we will decide which way to go. It would be great just to be off everything except for some clonazepam for a while. But, if the major depression strikes again, it can take weeks for Nardil or Parnate to kick back in. Just my latest story.
Take care you guys,
JediResearch:
Biol Psychiatry. 1993 Aug 1;34(3):146-51.
Spontaneous hypertensive reactions with monoamine oxidase inhibitors.
Lavin MR, Mendelowitz A, Kronig MH.
Department of Psychiatry, Hillside Hospital, Long Island Jewish Medical Center, Glen Oaks, NY.Despite long-standing concerns over hypertensive reactions, monoamine oxidase inhibitors (MAOIs) have grown in popularity and are now used in a variety of psychiatric disorders. The risk of hypertensive episodes is less than 1%. This is most likely the result of careful dietary instructions and prudent prescribing of concomitant medications. The possibility exists of spontaneous or unprovoked hypertensive crises in patients receiving MAOIs. In this report, we review the literature on spontaneous hypertensive episodes and present a case report. There has been a total of 11 cases described in six separate reports. We discuss the possible mechanism, risk factors, treatment, and safety of rechallenging the patients with the MAOI. Further research is needed to clarify this reaction. For now, it remains a rare but worrisome phenomenon. It should stand as an additional source of concern for clinicians who are already well aware of the risk of hypertensive episodes in patients receiving MAOIs.
J Clin Psychopharmacol. 1989 Feb;9(1):48-51. Links
Comment in:
J Clin Psychopharmacol. 1990 Jun;10(3):232.
Autoinduction of hypertensive reactions by tranylcypromine?
Keck PE Jr, Pope HG Jr, Nierenberg AA.
Laboratories for Psychiatric Research, Mailman Research Center, Belmont, Massachusetts.Although rarely described in the psychiatric literature, patients treated with monoamine oxidase inhibitors may experience acute hypertensive reactions that are not readily attributable to dietary indiscretion or use of concomitant medications. Four cases of apparent autoinduction of hypertensive reactions in patients receiving tranylcypromine are presented. The mechanism of this reaction is unknown, but may involve conversion of tranylcypromine to metabolites with pressor activity.
poster:Jedi
thread:760320
URL: http://www.dr-bob.org/babble/20070604/msgs/761196.html