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Re: Anyone else find ibuprofen mildly anxiolytic?

Posted by linkadge on May 9, 2007, at 11:13:45

In reply to Re: Anyone else find ibuprofen mildly anxiolytic? » Dunder, posted by Phillipa on May 9, 2007, at 10:57:21

Ibuprofen is also a mild-moderate inhibitor of FAAH. Fatty acid anandamide hydrogenase inhibitors slow the breakdown of the endocannabanoid anandamide. Anandamide is called the "bliss molecule" for its anxiolytic and serenic effects.

The degree to which clinical doses of ibuprofen increase anandamide is uncertain, but this is one possable mechanism to consider.

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