Posted by psychobot5000 on April 23, 2007, at 14:37:17
In reply to Re: Article: mood/ocd research with abused drugs » nellie7, posted by linkadge on April 23, 2007, at 14:09:50
> THe 5-ht2a/c receptors mediate gabergic responces in the frontal cortex. By activating these receptors one may help ameliorate the pathological frontal cortex activity that one sees in OCD.
>
> So no, there may actually be some theraputic utility to these drugs, beyond their recreactional effects.
>I would hope this research would lead to the development of drugs with less offensive side-effects (the hallucinations or whatever). I used to know someone who seemed OCD to me (no diagnosis as far as I know), and who used psilocybin frequently in his off hours--it seemed strangely like self-medication to me.
I believe we must also distinguish between 'psychedelic' effects and 'making them psychotic.' If I understand the issues right, I believe they are distinct phenomena, after all, and I'm not aware of psilocybin being associated with psychosis. ...When I was in college it had the reputation of being more of a relaxing, anxiolytic drug.
By the way, I believe it also is a 5-HT2b agonist--which would seem to mean a high risk of heart-valve damage.
poster:psychobot5000
thread:752704
URL: http://www.dr-bob.org/babble/20070419/msgs/752751.html